Electron microscopic cytochemistry of catecholaminergic innervation of LHRH neurons in the medial preoptic area of the rat.
نویسندگان
چکیده
The synaptic interactions between catecholaminergic terminals and luteinizing hormone releasing hormone (LHRH)-containing neurons in the medial preoptic area of the rat was studied by electron microscopy using LHRH immunocytochemistry combined with 5-hydroxydopamine labeling or autoradiography after injection of 3H-dopamine or 3H-noradrenaline in the same tissue section. Axon terminals labeled with 5-hydroxydopamine, 3H-dopamine or 3H-noradrenaline were found to make synapse-like contacts with LHRH-immunoreactive nerve cell bodies and fibers in the medial preoptic area and also 5-hydroxydopamine-labeled terminals made synaptic contacts with the same LHRH-immunoreactive nerve fibers with unlabeled terminals. These findings suggest that catecholaminergic neurons may innervate LHRH-containing neurons to regulate LHRH secretion via synapses with other unknown neurons in the medial preoptic area of the rat.
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ورودعنوان ژورنال:
- Archivum histologicum Japonicum = Nihon soshikigaku kiroku
دوره 50 1 شماره
صفحات -
تاریخ انتشار 1987